Bibliography

Bibliography

For more information or copies of journal articles, please contact info@bdmethylation.com.

ALCOHOL

 

 

PHILIBERT

 

A Comparison of the Predictive Power of DNA Methylation with Carbohydrate Deficient Transferrin for Heavy Alcohol Consumption.

Miller S, A Mills J, Long J, Philibert R. A Comparison of the Predictive Power of DNA Methylation with Carbohydrate Deficient Transferrin for Heavy Alcohol Consumption. Epigenetics. 2020 Oct 26:1-11.https://doi.org/10.1080/15592294.2020.1834918

 

A Four Marker Digital PCR Toolkit for Detecting Heavy Alcohol Consumption and the Effectiveness of Its Treatment.

Philibert R, Miller S, Noel A, et al. A Four Marker Digital PCR Toolkit for Detecting Heavy Alcohol Consumption and the Effectiveness of Its Treatment. J Insur Med. 2019;48(1):90-102. doi:10.17849/insm-48-1-1-1.1

 

Genome Wide and Digital PCR Epigenetic Assessments of Alcohol Consumption.

Philibert R, Dogan M, Noel A, et al. Genome-wide and digital polymerase chain reaction epigenetic assessments of alcohol consumption. Am J Med Genet B Neuropsychiatr Genet. 2018;177(5):479-488. doi:10.1002/ajmg.b.32636

 

A Review of Epigenetic Markers of Tobacco and Alcohol Consumption.

Philibert R, Erwin C. A Review of Epigenetic Markers of Tobacco and Alcohol Consumption. Behav Sci Law. 2015;33(5):675-690. doi:10.1002/bsl.2202

 

A Pilot Examination of the Genome-Wide DNA Methylation Signatures of Subjects Entering and Exiting Short-Term Alcohol Dependence Treatment Programs.

Philibert RA, Penaluna B, White T, et al. A pilot examination of the genome-wide DNA methylation signatures of subjects entering and exiting short-term alcohol dependence treatment programs. Epigenetics. 2014;9(9):1212-1219. doi:10.4161/epi.32252

Cited over 100 times

 

 The impact of recent alcohol use on genome wide DNA methylation signatures.

Philibert RA, Plume JM, Gibbons FX, Brody GH and Beach SRH (2012) The impact of recent alcohol use on genome wide DNA methylation signatures. Front. Gene. 3:54. doi: 10.3389/fgene.2012.00054

 

 

AFFILIATED

 

Current and Future Prospects for Epigenetic Biomarkers of Substance Use Disorders.

Andersen AM, Dogan MV, Beach SR, Philibert RA. Current and Future Prospects for Epigenetic Biomarkers of Substance Use Disorders. Genes (Basel). 2015;6(4):991‐1022. Published 2015 Oct 14. doi:10.3390/genes604099

INDEPENDENT

 

DNA Methylation Signatures of Chronic Alcohol Dependence in Puriced CD3+ T-Cells of Patients Undergoing Alcohol Treatment.

Brückmann C, Islam SA, MacIsaac JL, et al. DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients undergoing alcohol treatment. Sci Rep. 2017;7(1):6605. Published 2017 Jul 26. doi:10.1038/s41598-017-06847-z

 

Validation of Differential GDAP1 DNA Methylation in Alcohol Dependence and its Potential Function as a Biomarker for Disease Severity and Therapy Outcome.

Brückmann C, Di Santo A, Karle KN, Batra A, Nieratschker V. Validation of differential GDAP1 DNA methylation in alcohol dependence and its potential function as a biomarker for disease severity and therapy outcome. Epigenetics. 2016;11(6):456-463. doi:10.1080/15592294.2016.1179411

 

SMOKING

PHILIBERT

DNA methylation differentiates smoking from vaping and non-combustible tobacco use.

Andersen A, Reimer R, Dawes K, Becker A, Hutchens N, Miller S, Dogan M, Hundley B, A Mills J, D Long J, Philibert R. DNA methylation differentiates smoking from vaping and non-combustible tobacco use. Epigenetics. 2021 Feb 25:1-13. https://doi.org/10.1080/15592294.2021.1890875

 

Array-Based Epigenetic Aging Indices May Be Racially Biased.

Philibert R, Beach SRH, Lei M-K, Gibbons FX, Gerrard M, Simons RL, Dogan MV. Array-Based Epigenetic Aging Indices May Be Racially Biased. Genes. 2020; 11(6):685. https://doi.org/10.3390/genes11060685

The Reversion of cg05575921 Methylation in Smoking Cessation: A Potential Tool for Incentivizing Healthy Aging.

Philibert R, Mills JA, Long JD, Salisbury SE, Comellas A, Gerke A, Dawes K, Vander Weg M, Hoffman EA. The Reversion of cg05575921 Methylation in Smoking Cessation: A Potential Tool for Incentivizing Healthy Aging. Genes. 2020; 11(12):1415. https://doi.org/10.3390/genes11121415

AHRR methylation predicts smoking status and smoking intensity in both saliva and blood DNA.

Philibert R, Dogan M, Beach SRH, Mills JA, Long JD. AHRR methylation predicts smoking status and smoking intensity in both saliva and blood DNA. Am J Med Genet B Neuropsychiatr Genet. 2020;183(1):51-60. doi:10.1002/ajmg.b.32760

AHRR Methylation Is a Significant Predictor of Mortality Risk in Framingham Heart Study

Philibert RA, Dogan MV, Mills JA, Long JD. AHRR Methylation is a Significant Predictor of Mortality Risk in Framingham Heart Study. J Insur Med. 2019;48(1):79‐89. doi:10.17849/insm-48-1-1-11.1

Reversion of AHRR Demethylation Is a Quantitative Biomarker of Smoking Cessation.

Philibert R, Hollenbeck N, Andersen E, et al. Reversion of AHRR Demethylation Is a Quantitative Biomarker of Smoking Cessation. Front Psychiatry. 2016;7:55. Published 2016 Apr 6. doi:10.3389/fpsyt.2016.00055

A Quantitative Epigenetic Approach for the Assessment of Cigarette Consumption.

Philibert R, Hollenbeck N, Andersen E, et al. A quantitative epigenetic approach for the assessment of cigarette consumption. Front Psychol. 2015;6:656. Published 2015 Jun 2. doi:10.3389/fpsyg.2015.00656

Coordinated Changes in AHRR Methylation in Lymphoblasts and Pulmonary Macrophages from Smokers.

Monick MM, Beach SR, Plume J, et al. Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers. Am J Med Genet B Neuropsychiatr Genet. 2012;159B(2):141‐151. doi:10.1002/ajmg.b.32021

Cited over 200 times

Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking.

Philibert, R.A., Beach, S.R.H., Lei, M. et al. Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking. Clin Epigenet 5, 19 (2013). https://doi.org/10.1186/1868-7083-5-19

Cited over 100 times

The Effect of Tobacco Smoking Differs across Indices of DNA Methylation-Based Aging in an African American Sample: DNA Methylation-Based Indices of Smoking Capture These Effects.

Lei MK, Gibbons FX, Simons RL, Philibert RA, Beach SRH. The Effect of Tobacco Smoking Differs across Indices of DNA Methylation-Based Aging in an African American Sample: DNA Methylation-Based Indices of Smoking Capture These Effects. Genes (Basel). 2020;11(3):311. Published 2020 Mar 14. doi:10.3390/genes11030311

Cigarette and Cannabis Smoking Effects on GPR15+ Helper T Cell Levels in Peripheral Blood: Relationships with Epigenetic Biomarkers.

Andersen AM, Lei MK, Beach SRH, Philibert RA, Sinha S, Colgan JD. Cigarette and Cannabis Smoking Effects on GPR15+ Helper T Cell Levels in Peripheral Blood: Relationships with Epigenetic Biomarkers. Genes (Basel). 2020;11(2):149. Published 2020 Jan 30. doi:10.3390/genes11020149

AHRR methylation predicts smoking status and smoking intensity in both saliva and blood DNA.

Philibert R, Dogan M, Beach SRH, Mills JA, Long JD. AHRR methylation predicts smoking status and smoking intensity in both saliva and blood DNA. Am J Med Genet B Neuropsychiatr Genet. 2020;183(1):51-60. doi:10.1002/ajmg.b.32760

Saliva DNA Methylation Detects Nascent Smoking in Adolescents.

Dawes K, Andersen A, Vercande K, et al. Saliva DNA Methylation Detects Nascent Smoking in Adolescents. J Child Adolesc Psychopharmacol. 2019;29(7):535-544. doi:10.1089/cap.2018.0176

Dose Response and Prediction Characteristics of a Methylation Sensitive Digital PCR Assay for Cigarette Consumption in Adults.

Philibert R, Dogan M, Noel A, Miller S, Krukow B, Papworth E, Cowley J, Long JD, Beach SRH and Black DW (2018) Dose Response and Prediction Characteristics of a Methylation Sensitive Digital PCR Assay for Cigarette Consumption in Adults. Front. Genet. 9:137.

Accuracy and Utility of an Epigenetic Biomarker for Smoking in Populations with Varying Rates of False Self-Report.

Andersen AM, Philibert RA, Gibbons FX, Simons RL, Long J. Accuracy and utility of an epigenetic biomarker for smoking in populations with varying rates of false self-report. Am J Med Genet B Neuropsychiatr Genet. 2017;174(6):641-650. doi:10.1002/ajmg.b.32555

A Quantitative Epigenetic Approach for the Assessment of Cigarette Consumption. 

Philibert R, Hollenbeck N, Andersen E, et al. A quantitative epigenetic approach for the assessment of cigarette consumption. Front Psychol. 2015;6:656. Published 2015 Jun 2. doi:10.3389/fpsyg.2015.00656

 The Effect of Smoking on DNA Methylation of Peripheral Blood Mononuclear Cells from African American Women.

Dogan MV, Shields B, Cutrona C, et al. The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women. BMC Genomics. 2014;15:151. Published 2014 Feb 22. doi:10.1186/1471-2164-15-151

Changes in DNA Methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking.

Philibert RA, Beach SR, Lei MK, Brody GH. Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking. Clin Epigenetics. 2013;5(1):19. Published 2013 Oct 11. doi:10.1186/1868-7083-5-19

Demethylation of the Aryl Hydrocarbon Receptor Repressor as a Biomarker for Nascent Smokers.

Philibert RA, Beach SR, Brody GH. Demethylation of the aryl hydrocarbon receptor repressor as a biomarker for nascent smokers. Epigenetics. 2012;7(11):1331-1338. doi:10.4161/epi.22520

Coordinated DNA Methylation and Gene Expression Changes in Smoker Alveolar Macrophages: Specific Effects on VEGF Receptor 1 Expression.

Philibert RA, Beach SR, Brody GH. Demethylation of the aryl hydrocarbon receptor repressor as a biomarker for nascent smokers. Epigenetics. 2012;7(11):1331-1338. doi:10.4161/epi.22520

AFFILIATED

The Effect of Tobacco Smoking Differs across Indices of DNA Methylation-Based Aging in an African American Sample: DNA Methylation-Based Indices of Smoking Capture These Effects.

Lei MK, Gibbons FX, Simons RL, Philibert RA, Beach SRH. The Effect of Tobacco Smoking Differs across Indices of DNA Methylation-Based Aging in an African American Sample: DNA Methylation-Based Indices of Smoking Capture These Effects. Genes (Basel). 2020;11(3):311. Published 2020 Mar 14. doi:10.3390/genes11030311

Saliva DNA Methylation Detects Nascent Smoking in Adolescents.

Dawes K, Andersen A, Vercande K, Papworth E, Philibert W, Beach SRH, Gibbons FX, Gerrard M, Philibert R.

J Child Adolesc Psychopharmacol. 2019 Aug;29(7):535-544. doi: 10.1089/cap.2018.0176. Epub 2019 Jun 10.

A Droplet Digital PCR Assay for Smoking Predicts All-Cause Mortality.

Andersen AM, Ryan PT, Gibbons FX, Simons RL, Long JD, Philibert RA. A Droplet Digital PCR Assay for Smoking Predicts All-Cause Mortality. J Insur Med. 2018;47(4):220-229. doi:10.17849/insm-47-4-1-10.1

INDEPENDENT

Validated Inference of Smoking Habits From Blood With a Finite DNA Methylation Marker Set

Maas SCE, Vidaki A, Wilson R, et al. Validated inference of smoking habits from blood with a finite DNA methylation marker set. Eur J Epidemiol. 2019;34(11):1055‐1074. doi:10.1007/s10654-019-00555-w

AHRR (cg05575921) Hypomethylation Marks Smoking Behaviour, Morbidity and Mortality

Bojesen SE, Timpson N, Relton C, Davey Smith G, Nordestgaard BG. AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality. Thorax. 2017;72(7):646‐653. doi:10.1136/thoraxjnl-2016-208789

Smoking-Associated DNA Methylation Biomarkers and Their Predictive Value for All-Cause and Cardiovascular Mortality.

Zhang Y, Schöttker B, Florath I, et al. Smoking-Associated DNA Methylation Biomarkers and Their Predictive Value for All-Cause and Cardiovascular Mortality. Environ Health Perspect. 2016;124(1):67‐74. doi:10.1289/ehp.1409020

DNA Methylation Changes of Whole Blood Cells in Response to Active Smoking Exposure in Adults: A Systematic Review of DNA Methylation Studies.

Gao X, Jia M, Zhang Y, Breitling LP, Brenner H. DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies. Clin Epigenetics. 2015;7:113. Published 2015 Oct 16. doi:10.1186/s13148-015-0148-3

 DNA Methylation as a Long-Term Biomarker of Exposure to Tobacco Smoke.

Shenker NS, Ueland PM, Polidoro S, et al. DNA methylation as a long-term biomarker of exposure to tobacco smoke. Epidemiology. 2013;24(5):712-716. doi:10.1097/EDE.0b013e31829d5cb3

Epigenome-wide association study in the European prospective investigation into cancer and nutrition (EPIC-TURIN) identifies novel genetic loci associated with smoking.

Shenker NS, Polidoro S, van Veldhoven K, et al. Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking. Hum Mol Genet. 2013;22(5):843-851. doi:10.1093/hmg/dds488

 450K Epigenome-wide scan identifies differential DNA Methylation in newborns related to maternal smoking during pregnancy.

Joubert BR, Håberg SE, Nilsen RM, et al. 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy [published correction appears in Environ Health Perspect. 2012 Dec;120(12):A455]. Environ Health Perspect. 2012;120(10):1425-1431. doi:10.1289/ehp.1205412

ALL-CAUSE MORTALITY

PHILIBERT

 

 A simple, rapid, interpretable, actionable and implementable digital PCR based mortality index.

Philibert R, Long JD, Mills JA, Beach SRH, Gibbons FX, Gerrard M, Simons R, Pinho PB, Ingle D, Dawes K, Dogan T, Dogan M. A simple, rapid, interpretable, actionable and implementable digital PCR based mortality index. Epigenetics. 2020 Nov 2:1-15. https://doi.org/10.1080/15592294.2020.1841874

 

 AHRR Methylation is a Significant Predictor of Mortality Risk in Framingham Heart Study.

Philibert RA, Dogan MV, Mills JA, Long JD. AHRR Methylation is a Significant Predictor of Mortality Risk in Framingham Heart Study. J Insur Med. 2019;48(1):79-89. doi:10.17849/insm-48-1-1-11.1

A Direct Comparison of the Relationship of Epigenetic Aging and Epigenetic Substance Consumption Markers to Mortality in the Framingham Heart Study

Mills JA, Beach SRH, Dogan M, et al. A Direct Comparison of the Relationship of Epigenetic Aging and Epigenetic Substance Consumption Markers to Mortality in the Framingham Heart Study. Genes (Basel). 2019;10(1):51. Published 2019 Jan 15. doi:10.3390/genes10010051

A Droplet Digital PCR Assay for Smoking Predicts All-Cause Mortality

Andersen AM, Ryan PT, Gibbons FX, Simons RL, Long JD, Philibert RA. A Droplet Digital PCR Assay for Smoking Predicts All-Cause Mortality. J Insur Med. 2018;47(4):220-229. doi:10.17849/insm-47-4-1-10.1