Bibliography

Bibliography

For more information or copies of journal articles, please contact info@bdmethylation.com.

 

 

 

 

 

 

 

Alcohol

 

 

Philibert

The impact of recent alcohol use on genome wide DNA methylation signatures

Philibert RA, Plume JM, Gibbons FX, Brody GH and Beach SRH (2012) The impact of recent alcohol use on genome wide DNA methylation signatures. Front. Gene. 3:54. doi: 10.3389/fgene.2012.00054

Cited over 100 times

 

A Review of Epigenetic Markers of Tobacco and Alcohol Consumption

Philibert R, Erwin C. A Review of Epigenetic Markers of Tobacco and Alcohol Consumption. Behav Sci Law. 2015;33(5):675‐690. doi:10.1002/bsl.2202

 

 

A Four Marker Digital PCR Toolkit for Detecting Heavy Alcohol Consumption and the Effectiveness of Its Treatment.

Philibert R, Miller S, Noel A, Dawes K, Papworth E, Black DW, Beach SRH, Long JD, Mills JA, Dogan M.

J Insur Med. 2019;48(1):90-102. doi: 10.17849/insm-48-1-1-1.1. Epub 2019 Oct 14.

 

AHRR methylation predicts smoking status and smoking intensity in both saliva and blood DNA.

Philibert R, Dogan M, Beach SRH, Mills JA, Long JD.

Am J Med Genet B Neuropsychiatr Genet. 2020 Jan;183(1):51-60. doi: 10.1002/ajmg.b.32760. Epub 2019 Aug 27.

 

Genome Wide and Digital PCR Epigenetic Assessments of Alcohol Consumption

Philibert, Robert; Dogan, Meeshanthini; Noel, Amanda; Miller, Shelly;  Krukow, Brianna; Cowley, Joseph; Knudsen, April; Beach, Steven; Black, Donald W.

Genome wide and Digital PCR Epigenetic Assessments of Alcohol Consumption. American Journal of Medical Genetics

 

A Pilot Examination of the Genome-Wide DNA Methylation Signatures of Subjects Entering and Exiting Short-Term Alcohol Dependence Treatment Programs

Philibert RA, Penaluna B, White T, Shires S, Gunter T, Liesveld J, Erwin C, Hollenbeck N, Osborn T. 2014.

A pilot examination of the genome-wide DNA methylation signatures of subjects entering and exiting short-term alcohol dependence treatment programs. Epigenetics 9:9:1212-1219. PMID:25147915.

 

 

Affiliated

 

 

 

 

Independent

 

DNA METHYLATION SIGNATURES OF CHRONIC ALCOHOL DEPENDENCE IN PURIFIED CD3+ T-CELLS OF PATIENTS UNDERGOING ALCOHOL TREATMENT.

Brückmann C, Islam SA, MacIsaac JL, Morin AM, Karle KN, Santo AD, Wüst R, Lang I, Batra A, Kobor MS, Nieratschker V. 2017.

DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients undergoing alcohol treatment

 

VALIDATION OF DIFFERENTIAL GDAP1 DNA METHYLATION IN ALCOHOL DEPENDENCE AND ITS POTENTIAL FUNCTION AS A BIOMARKER FOR DISEASE SEVERITY AND THERAPY OUTCOME.

Brückmann C, Santo AD, Karle KN, Batra A, Nieratschker V. 2016. Validation of differential GDAP1 DNA methylation in alcohol dependence and its potential function as a biomarker for disease severity and therapy outcome. Epigenetics 11:6. PMID:27128683.

 

 

Smoking

 

 

Philibert

Smoking-Associated DNA Methylation Biomarkers and Their Predictive Value for All-Cause and Cardiovascular MortalityZhang Y, Schöttker B, Florath I, et al. Smoking-Associated DNA Methylation Biomarkers and Their Predictive Value for All-Cause and Cardiovascular Mortality. Environ Health Perspect. 2016;124(1):67‐74. doi:10.1289/ehp.1409020

 

A Quantitative Epigenetic Approach for the Assessment of Cigarette Consumption

Philibert R, Hollenbeck N, Andersen E, et al. A quantitative epigenetic approach for the assessment of cigarette consumption. Front Psychol. 2015;6:656. Published 2015 Jun 2. doi:10.3389/fpsyg.2015.00656

 

Validated Inference of Smoking Habits From Blood With a Finite DNA Methylation Marker Set

Maas SCE, Vidaki A, Wilson R, et al. Validated inference of smoking habits from blood with a finite DNA methylation marker set. Eur J Epidemiol. 2019;34(11):1055‐1074. doi:10.1007/s10654-019-00555-w

 

Reversion of AHRR Demethylation Is a Quantitative Biomarker of Smoking Cessation

Philibert R, Hollenbeck N, Andersen E, et al. Reversion of AHRR Demethylation Is a Quantitative Biomarker of Smoking Cessation. Front Psychiatry. 2016;7:55. Published 2016 Apr 6. doi:10.3389/fpsyt.2016.00055

 

AHRR Methylation Is a Significant Predictor of Mortality Risk in Framingham Heart Study

Philibert RA, Dogan MV, Mills JA, Long JD. AHRR Methylation is a Significant Predictor of Mortality Risk in Framingham Heart Study. J Insur Med. 2019;48(1):79‐89. doi:10.17849/insm-48-1-1-11.1

 

AHRR (cg05575921) Hypomethylation Marks Smoking Behaviour, Morbidity and Mortality

Bojesen SE, Timpson N, Relton C, Davey Smith G, Nordestgaard BG. AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality. Thorax. 2017;72(7):646‐653. doi:10.1136/thoraxjnl-2016-208789

 

Coordinated Changes in AHRR Methylation in Lymphoblasts and Pulmonary Macrophages from Smokers  

Monick MM, Beach SR, Plume J, et al. Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers. Am J Med Genet B Neuropsychiatr Genet. 2012;159B(2):141151. doi:10.1002/ajmg.b.32021

Cited over 200 times

 

Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking

Philibert, R.A., Beach, S.R.H., Lei, M. et al. Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking. Clin Epigenet 5, 19 (2013). https://doi.org/10.1186/1868-7083-5-19

 

The Effect of Tobacco Smoking Differs across Indices of DNA Methylation-Based Aging in an African American Sample: DNA Methylation-Based Indices of Smoking Capture These Effects.

Lei MK, Gibbons FX, Simons RL, Philibert RA, Beach SRH.

Genes (Basel). 2020 Mar 14;11(3). pii: E311. doi: 10.3390/genes11030311.

 

Cigarette and Cannabis Smoking Effects on GPR15+ Helper T Cell Levels in Peripheral Blood: Relationships with Epigenetic Biomarkers.

Andersen AM, Lei MK, Beach SRH, Philibert RA, Sinha S, Colgan JD.

Genes (Basel). 2020 Jan 30;11(2). pii: E149. doi: 10.3390/genes11020149.

 

Philibert R, Dogan M, Beach SRH, Mills JA, Long JD. AHRR methylation predicts smoking status and smoking intensity in both saliva and blood DNA. Am J Med Genet B Neuropsychiatr Genet. 2020 Jan;183(1):51-60. doi: 10.1002/ajmg.b.32760. Epub

2019 Aug 27. PubMed PMID: 31456352.

 

Saliva DNA Methylation Detects Nascent Smoking in Adolescents.

Dawes K, Andersen A, Vercande K, Papworth E, Philibert W, Beach SRH, Gibbons FX, Gerrard M, Philibert R.

J Child Adolesc Psychopharmacol. 2019 Aug;29(7):535-544. doi: 10.1089/cap.2018.0176. Epub 2019 Jun 10.

 

DOSE RESPONSE AND PREDICTION CHARACTERISTICS OF A METHYLATION SENSITIVE DIGITAL PCR ASSAY FOR CIGARETTE CONSUMPTION IN ADULTS

Robert Philibert, Meeshanthini Dogan, Amanda Noel, Shelly Miller, Brianna Krukow, Emma Papworth, Joseph Cowley, Jeffrey D. Long and Donald W. Black, University of Iowa, United States, Behavioral Diagnostics LLC, United States, Cardio Diagnostics, United States, Center for Alcohol and Drug Services, United States

 

ACCURACY AND UTILITY OF AN EPIGENETIC BIOMARKER FOR SMOKING IN POPULATIONS WITH VARYING RATES OF FALSE SELF-REPORT

Andersen AM, Philibert RA, Gibbons FX, Simons RL, Long J. Accuracy and utility of an epigenetic biomarker for smoking in populations with varying rates of false self-report. Am J Med Genet Part B. 2017; 9999:1–10.

 

A QUANTITATIVE EPIGENETIC APPROACH FOR THE ASSESSMENT OF CIGARETTE CONSUMPTION.

Philibert R, Hollenbeck N, Andersen E, Osborn T, Gerrard M, Gibbons FX, Wang K. 2015. A quantitative epigenetic approach for the assessment of cigarette consumption. Frontiers in Psychology 6:656. PMID:26082730

 

DEMETHYLATION OF THE ARYL HYDROCARBON RECEPTOR REPRESSOR AS A BIOMARKER FOR NASCENT SMOKERS.

Philibert R, Beach SR, Brody GH. 2012. Demethylation of the aryl hydrocarbon receptor repressor as a biomarker for nascent smokers.  Epigenetics 7:1331-1338.  PMID:23070629.

 

COORDINATED DNA METHYLATION AND GENE EXPRESSION CHANGES IN SMOKER ALVEOLAR MACROPHAGES: SPECIFIC EFFECTS ON VEGF RECEPTOR 1 EXPRESSION.

Philibert RA, Sears RA, Powers LS, Nash E, Bair T, Gerke AK, … Monick MM. 2012. Coordinated DNA methylation and gene expression changes in smoker alveolar macrophages: specific effects on VEGF receptor 1 expression. Journal of Leukocyte Biology 92(3):621–631. PMID:22427682.

 

COORDINATED CHANGES IN AHRR METHYLATION IN LYMPHOBLASTS AND PULMONARY MACROPHAGES FROM SMOKERS.

Monick MM, Beach SRH, Plume J, Sears R, Gerrard M, Brody GH, Philibert RA. 2012. Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers. American Journal of Medical Genetics 159B(2):141–151. PMID:22232023.

 

CHANGES IN DNA METHYLATION AT THE ARYL HYDROCARBON RECEPTOR REPRESSOR MAY BE A NEW BIOMARKER FOR SMOKING.

Philibert RA, Beach SRH, Lei MK, Brody GH. 2013. Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking. Clinical Epigenetics 5(1):19. PMID:24120260.

 

THE EFFECT OF SMOKING ON DNA METHYLATION OF PERIPHERAL BLOOD MONONUCLEAR CELLS FROM AFRICAN AMERICAN WOMEN.

Dogan MV, Shields B, Cutrona C, Gao L, Gibbons FX, Simons R, … Philibert RA. 2014. The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women. BMC Genomics 15:151. PMID:24559495.

 

 

Affiliated

 

The Effect of Tobacco Smoking Differs across Indices of DNA Methylation-Based Aging in an African American Sample: DNA Methylation-Based Indices of Smoking Capture These Effects.

Lei MK, Gibbons FX, Simons RL, Philibert RA, Beach SRH.

Genes (Basel). 2020 Mar 14;11(3). pii: E311. doi: 10.3390/genes11030311.

 

Saliva DNA Methylation Detects Nascent Smoking in Adolescents.

Dawes K, Andersen A, Vercande K, Papworth E, Philibert W, Beach SRH, Gibbons FX, Gerrard M, Philibert R.

J Child Adolesc Psychopharmacol. 2019 Aug;29(7):535-544. doi: 10.1089/cap.2018.0176. Epub 2019 Jun 10.

 

A Droplet Digital PCR Assay for Smoking Predicts All-Cause Mortality.

Andersen AM, Ryan PT, Gibbons FX, Simons RL, Long JD, Philibert RA.

J Insur Med. 2018;47(4):220-229. doi: 10.17849/insm-47-4-1-10.1. Epub 2019 Jan 31.

 

 

Independent

 

450K EPIGENOME-WIDE SCAN IDENTIFIES DIFFERENTIAL DNA METHYLATION IN NEWBORNS RELATED TO MATERNAL SMOKING DURING PREGNANCY

Joubert BR, Håberg SE, Nilsen RM, Wang X, Vollset SE, Murphy SK, Huang Z, Hoyo C, Midttun Ø, Cupul-Uicab LA, Ueland PM, Wu MC, Nystad W, Bell DA, Peddada SD, London SJ. 2012. 450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal…

 

DNA METHYLATION AS A LONG-TERM BIOMARKER OF EXPOSURE TO TOBACCO SMOKE.

Shenker NS, Ueland, PM, Polidoro S, van Veldhoven K, Ricceri F, Brown R, Flanagan JM, Vineis P, Flanagan JM.  2013.  DNA Methylation as a long-term biomarker of exposure to tobacco smoke.  Epidemiology 24:712-716. PMID:23867811.

 

DNA METHYLATION CHANGES OF WHOLE BLOOD CELLS IN RESPONSE TO ACTIVE SMOKING EXPOSURE IN ADULTS: A SYSTEMATIC REVIEW OF DNA METHYLATION STUDIES.

Gao X, Jia M, Zhang Y, Breitling LP, Brenner H. 2015. DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies. Clinical Epigenetics 7:113. PMC4609112

 

EPIGENOME-WIDE ASSOCIATION STUDY IN THE EUROPEAN PROSPECTIVE INVESTIGATION INTO CANCER AND NUTRITION (EPIC-TURIN) IDENTIFIES NOVEL GENETIC LOCI ASSOCIATED WITH SMOKING.

Shenker NS, Polidoro S, van Veldhoven K, Sacerdote C, Ricceri F, Birrell MA, Belvisi MG, Brown R, Vineis P, Flanagan JM. 2012.  Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking. Human Molecular Genetics….

 

 

All-Cause Mortality

 

 

Philibert

 

 

 

 

AHRR Methylation is a Significant Predictor of Mortality Risk in Framingham Heart Study.

Philibert RA, Dogan MV, Mills JA, Long JD.

J Insur Med. 2019;48(1):79-89. doi: 10.17849/insm-48-1-1-11.1. Epub 2019 Oct 16.

 

Philibert RA, Dogan MV, Mills JA, Long JD. AHRR Methylation is a Significant Predictor of Mortality Risk in Framingham Heart Study. J Insur Med. 2019;48(1):79-89. doi: 10.17849/insm-48-1-1-11.1. Epub 2019 Oct 16. PubMed PMID:  31618096.

 

Andersen AM, Ryan PT, Gibbons FX, Simons RL, Long JD, Philibert RA. A Droplet Digital PCR Assay for Smoking Predicts All-Cause Mortality. J Insur Med. 2018;47(4):220-229. doi: 10.17849/insm-47-4-1-10.1. Epub 2019 Jan 31. PubMed PMID: 30702368.

 

Mills JA, Beach SRH, Dogan M, Simons RL, Gibbons FX, Long JD, Philibert R. A Direct Comparison of the Relationship of Epigenetic Aging and Epigenetic Substance Consumption Markers to Mortality in the Framingham Heart Study. Genes (Basel). 2019 Jan 15;10(1). pii: E51. doi: 10.3390/genes10010051. PubMed PMID: 30650672; PubMed Central PMCID: PMC6356614.