The scientific principles underlying our patented and patent-pending tests have been extensively validated in dozens of works by a number of research groups including our home group in Iowa. This listing includes our publications as well as selected publications from the more than 50 publications that have reproduced our results.
Joubert BR, Håberg SE, Nilsen RM, Wang X, Vollset SE, Murphy SK, Huang Z, Hoyo C, Midttun Ø, Cupul-Uicab LA, Ueland PM, Wu MC, Nystad W, Bell DA, Peddada SD, London SJ. 2012. 450K Epigenome-Wide Scan Identifies Differential D...
Philibert RA, Penaluna B, White T, Shires S, Gunter T, Liesveld J, Erwin C, Hollenbeck N, Osborn T. 2014. A pilot examination of the genome-wide DNA methylation signatures of subjects entering and exiting short-term alcohol d...
Philibert R, Hollenbeck N, Andersen E, Osborn T, Gerrard M, Gibbons FX, Wang K. 2015. A quantitative epigenetic approach for the assessment of cigarette consumption. Frontiers in Psychology 6:656. PMID:26082730 Link: https://...
Andersen AM, Philibert RA, Gibbons FX, Simons RL, Long J. Accuracy and utility of an epigenetic biomarker for smoking in populations with varying rates of false self-report. Am J Med Genet Part B. 2017; 9999:1–10. Link: http:...
Philibert RA, Beach SRH, Lei MK, Brody GH. 2013. Changes in DNA methylation at the aryl hydrocarbon receptor repressor may be a new biomarker for smoking. Clinical Epigenetics 5(1):19. PMID:24120260. Link: https://www.ncbi.nl...
Monick MM, Beach SRH, Plume J, Sears R, Gerrard M, Brody GH, Philibert RA. 2012. Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers. American Journal of Medical Genetics 159B(2):141...
Philibert RA, Sears RA, Powers LS, Nash E, Bair T, Gerke AK, … Monick MM. 2012. Coordinated DNA methylation and gene expression changes in smoker alveolar macrophages: specific effects on VEGF receptor 1 expression. Journal o...
Philibert R, Beach SR, Brody GH. 2012. Demethylation of the aryl hydrocarbon receptor repressor as a biomarker for nascent smokers. Epigenetics 7:1331-1338. PMID:23070629. Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC...
Shenker NS, Ueland, PM, Polidoro S, van Veldhoven K, Ricceri F, Brown R, Flanagan JM, Vineis P, Flanagan JM. 2013. DNA Methylation as a long-term biomarker of exposure to tobacco smoke. Epidemiology 24:712-716. PMID:238678...
Gao X, Jia M, Zhang Y, Breitling LP, Brenner H. 2015. DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies. Clinical Epigenetics 7:113. ...
Brückmann C, Islam SA, MacIsaac JL, Morin AM, Karle KN, Santo AD, Wüst R, Lang I, Batra A, Kobor MS, Nieratschker V. 2017. DNA methylation signatures of chronic alcohol dependence in purified CD3+ T-cells of patients underg...
Shenker NS, Polidoro S, van Veldhoven K, Sacerdote C, Ricceri F, Birrell MA, Belvisi MG, Brown R, Vineis P, Flanagan JM. 2012. Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrit...
Dogan MV, Shields B, Cutrona C, Gao L, Gibbons FX, Simons R, … Philibert RA. 2014. The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women. BMC Genomics 15:151. PMID:24559495...
Brückmann C, Santo AD, Karle KN, Batra A, Nieratschker V. 2016. Validation of differential GDAP1 DNA methylation in alcohol dependence and its potential function as a biomarker for disease severity and therapy outcome. Epigen...